IMMUNOGOLD LOCALIZATION OF GFAP AND MDR1 IN SURGICALLY RESECTED BRAIN TISSUES FROM CLINICAL INTRACTABLE EPILEPSY PATIENTS BY TRANSMISSION ELECTRON MICROSCOPY / 解剖学报
Acta Anatomica Sinica
; (6)2002.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-572841
Biblioteca responsável:
WPRO
ABSTRACT
Objective To determine the ultrastructural localization of MDR1 and GFAP in the surgically resected brain tissues from intractable epilepsy patients. Methods Expression of MDR1 and GFAP in brain tissues was examined by using PAG immunolabeling technique for electron microscopy. Results The MDR1 and GFAP labeled by gold particles were only detected at some reactive astrocytes. The positive gold particles were mainly located in the astrocytic cytoplasm and their membrane, but not in the nucleus.Conclusion The expression of MDR1 and GFAP in the brain of patients with clinically intractable epilepsy were mainly located at the cytoplasm and membrane of certain reactive astrocytics.;
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Acta Anatomica Sinica
Ano de publicação:
2002
Tipo de documento:
Artigo