Dissolution in vitro of tetrandrine coated on nickle-titandrine alloy stent / 中成药
Chinese Traditional Patent Medicine
; (12)1992.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-573449
Biblioteca responsável:
WPRO
ABSTRACT
AIM:
To prepare a nickle-titandrine alloy stent which was coated by tetrandrine from Radir stephaniae Tetrandrae and study its dissolution in vitro.METHODS:
Tetradrine velease from the stent was determined by ultra-violet spectrophotometry.RESULTS:
The drug releases from the stent with a equation of log(100-Rn)=- 0.0115t + 2.1730 (t=0~168 h),r= 0.9805 ,T 50 = 41.39 h,T d= 53.01 ,Kr= 0.0115 (h 1).CONCLUSION:
The drug released from the stent followed first-order model kinetics. The result of tetrandrine release exhibited ideal sustanined release characteristics. The stent was suitable for clinical application.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
Idioma:
Chinês
Revista:
Chinese Traditional Patent Medicine
Ano de publicação:
1992
Tipo de documento:
Artigo