THE ROLES OF SYMPATHETIC NERVE ON EMBRYO IMPLANTATION AND LOCAL IMMUNITY IN UTERUS OF MICE / 解剖学报

ABSTRACT

Objective To explore the effect mechanism of sympathetic nerve on early developing embryo of mice. Methods The model of sympathectomy mouse was established by 6-OHDA injected intraperitoneally.The early developing mice embryo and lymphocytes in uterus were observed using histology,immunohistochemistry and ELISA methods. Results In sympathectomy mouse,the number of embryo implantation was decrease to 64.4%,endometrial lamina propria and vascellum were shortfall.The numbers of CD4~+T cell and CD8~+T cell in sympathectomy mice were larger than ones in control groups,especially,the number of CD8~+T cells at E3 and E5 differed highly(P