A Metastatic Granulocyte Colony-Stimulating Factor Producing Sarcomatoid Carcinoma of the Lung Causing Jejunal Intussusception: Report of a Case
Korean Journal of Pathology
; : 205-208, 2011.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-58374
Biblioteca responsável:
WPRO
ABSTRACT
A 75-year-old man was referred to our hospital with intestinal obstruction caused by intussusception. Abdominal computed tomography (CT) revealed seven polypoid masses in the small intestine, while chest CT revealed a mass in the right lower lobe. Preoperative laboratory tests showed white blood cell (WBC) and neutrophil differential counts of 63,630/mm3 and 95%, respectively. The serum granulocyte colony-stimulating factor (G-CSF) was 114 pg/mL, which was elevated (normal range, <18.1 pg/mL). After resection of the small bowel, the WBC count decreased to 20,510/mm3. The pathology showed a poorly differentiated carcinoma with sarcomatous components confirmed by positive immunostaining of cytokeratin (AE1/AE3) and vimentin in the small intestine. Furthermore, immunohistochemistry with specific monoclonal antibodies against G-CSF was positive. A lung biopsy revealed the same histological findings as the small intestine lesion. Therefore, the patient was diagnosed as having a G-CSF producing sarcomatoid carcinoma of the lung with metastasis to the small intestine.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Tórax
/
Vimentina
/
Biópsia
/
Imuno-Histoquímica
/
Carcinossarcoma
/
Fator Estimulador de Colônias de Granulócitos
/
Granulócitos
/
Obstrução Intestinal
/
Intestino Delgado
/
Intussuscepção
Limite:
Idoso
/
Humanos
Idioma:
Inglês
Revista:
Korean Journal of Pathology
Ano de publicação:
2011
Tipo de documento:
Artigo