Treatment of body surface venous malformations by local injection of Pingyangmycin lipiodol emulsion under fluoroscopic guidance / 医学研究生学报

ABSTRACT

Objective: To evaluate the method,efficacy and complication of fluoroscopic guided local injection of Pingyangmycin lipiodol emulsion(PLE) in the treatment of body surface venous malformations(VM).Methods:Forty cases of VM,including 22 cases in the maxillofacial region,5 cases in the trunk and 13 cases in the extremities,received PLE local injection under X-ray fluoroscopy.PLE was prepared by mixing 2-8 mg of pingyangmycin(PYM)with 2-8ml of ultra-fluid lipiodol,the dosage was determined by the size of lesions.The effects and complications of PLE treatment were observed. Results:Signs of VM were patches of abnormal venous opacification and washout delay of contrast medium.Thirty four cases received single injection of PLE and 6 cases were injected twice.Excellent and good results were obtained in 20 cases and 16 cases respectively after 6 months post-injection,the therapy was ineffective in the rest four cases.Total efficacy was 90 percent.There were no severe complications such as skin necrosis or ectopic embolization. Conclusion: PLE intra-vascular injection under fluoroscopic guidance was convenient and safe for body surface VM.The merits of PLE treatment include accurate(localization,) safety,and excellent curative effect.