Structure and properties of tissue-engineered skin / 中国组织工程研究

ABSTRACT

In the human body, the structure of the organ and tissue is its functional foundation. With the human body skin losing, the skin also loses its function. When the skin defect area is quite large, it is the question that the source of the autologous skin is deficient. But with the engineering research progressing, the application of artificial skin to repair the skin defect is possible. In order to make the tissue-engineered skin have "normal" skin function, the structure research also should make them approach as far as possible to be similar. This article reviews the constructs, properties and applications of the epidermal substitutes, the dermal substitutes and the skin substitutes. With continued development of multi-discipline and continued progress of basic and clinical research, the constituted tissue-engineered skin substitutes will more approach the normal skin in the structure and properties.