Antibiotics Resistance Analysis for Escherichia coli in Traditional Chinese MedicineHospital / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To investigate drug-resistance status and changing tendency of Escherichia coli in traditional Chinese medicine hospital to provide the evidence for reasonable use of antibiotics.METHODS Pathogenic bacteria were isolated and identified according to the National Clinical Laboratory Operation Rules.Drug resistance profile was analyzed by K-B methods.RESULTS In the four years,the resistance to seventeen commonly used antibiotics in E.coli was on the rise.The resistance rate to ampicillin was the most highest(90.8-94.2%).No strain was resistant to imipenem and meropenem.the detection rate of extended spectrum ?-lactamases(ESBLs) producing E.coli was increasing from 13.2% to 32.0%.CONCLUSIONS Drug-resistance status of E.coli in traditional Chinese medicine hospital is very serious.We should strengthen the management of antibiotic use and control the spread and prevalence of the drug-resistant bacteria.