Expressions of P16 and proliferating cell nuclear antigen in osteosarcoma and clinical significances / 吉林大学学报(医学版)
Article
em Zh
| WPRIM
| ID: wpr-594866
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate the relationship between the expressions of P16 and proliferating cell nuclear antigen(PCNA) in osteosarcoma and clinicopathological features,and explore the effects of them in occurrence and development of osteosarcoma.Methods The expressions of P16 and PCNA were detected by immunohistochemistry(SP) in 71 osteosarcima tissues and 10 normal bone tissues.Results ①The positive rate of P16 expression in osteosarcoma tissues was lower than that in normal bone tissues(P0.05).The expression of PCNA had positive relationship with osteosarcoma's prognosis(P0.05).③There was negative correlation between P16 and PCNA expressions(rs=-0.58,P
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1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of Jilin University(Medicine Edition)
Ano de publicação:
2006
Tipo de documento:
Article