Drug-resistance of Klebsiella pneumoniae in Mountain Hospitals / 中华医院感染学杂志

ABSTRACT

OBJECTIVE To investigate the drug-resistance status of Klebsiella pneumoniae(KPN) in mountain hospitals and provide the reference for rational application of antibiotics.METHODS Referring to Rules of Operation in Clincal Laboratory of Nationwide,146 KPN isolates were cultured and identified and the drug-sensitivity test was performed in our hospital.RESULTS 100% of KPN isolates were sensitive to imipenem and meropenem.The resistant rates to amikacin,piperacillin/tazobactam,cefoperazone/sulbactam and cefoxitin were all below 22.0%.And that to the other 11 antibiotics were higher and all above 30%.The detection rate of the extended-spectrum-?-lactamases(ESBLs) producing KPN was 28.8%.CONCLUSIONS The drug-resistance of KPN in mountain hospitals is obviously lower than that in general hospitals of developed cities.We should strengthen reasonable management of antibiotics to prevent and control the occurrence and dissemination of drug resistant strains.