Determination of strychnine and brucine in maqianzi san by RP-HPLC / 中国药学杂志
Chinese Pharmaceutical Journal
; (24): 167-1998.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-598311
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
To develop a HPLC method for assaying strychnine and brucine in traditional Chinese drug Maqianzi San.METHODS:
With μBondapak C18 (10 μm) column (4 mm×300 mm), MeOH-H2O-HAc-(C2H5)3N(70∶230∶2.4∶0.3) as mobile phase, we set a detector at 254 nm.RESULTS:
Linear range of strychnine and brucine was 0.367 2 μg~0.061 2 μg and 0.945 0 μg~0.157 5 μg respectively. The recovery rate of strychnine and brucine was 100.36% (RSD=1.09%) and 100.01% (RSD=1.46%) respectively.CONCLUSION:
This method provides a simple and feasible way to control the quality of Maqianzi San.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Pharmaceutical Journal
Ano de publicação:
1998
Tipo de documento:
Artigo