Intraductal Papillomas of the Breast：the Potential Cause of Misdiagnosis of Shear Wave Elastography in Diagnosis of Benign and Malignant Breast Lesions / 中国医学影像学杂志

ABSTRACT

PurposeTo evaluate the shear wave elastography in diagnosis of intraductal papillomas, benign or malignant breast lesions.Materials and Methods From December 2013 to December 2014, 145 female patients with 155 lesions who underwent ultrasonography and shear wave elastography in general hospital of PLA were retrospectively studied. All the lesions were confirmed by pathology via surgery or biopsy. The performance of the maximum elasticity, the mean elasticity, the minimum elasticity values and the elasticity ratio in diagnosis of benign and malignant tumors were analyzed. The portion of intraductal papillomas in misdiagnosed cases was calculated. The elasticity values of intraductal papillomas were compared with those of other breast benign and malignant lesions.ResultsAmong 155 lesions, pathology confirmed intraductal papillomas in 20 lesions, fibroadenosis in 23 lesions, fibroadenoma in 23 lesions, inflammation in 9 lesions, adenosis with fibroadenoma in 17 lesions, and breast cancer in 63 lesions. The maximum, mean, minimum elasticity values and the elasticity ratio of intraductal papillomas were (84.39±74.08) kPa, (51.33±46.36) kPa, (26.55±24.98) kPa and 2.80±2.18, respectively. The elasticity values of intraductal papillomas were between those of breast cancer and other benign lesions, and there were no statistically significant (P=0.003).ConclusionThe elasticity values of intraductal papillomas were between those of breast cancer and other benign lesions, which may be a potential reason to cause misdiagnosis using shear wave elastography to differentiate breast benign and malignant diseases.