Efficacy and Safety Observation of Ferrous Succinate in the Treatment of Pregnancy Complicated with Iron Deficiency Anemia / 中国药房

ABSTRACT

OBJECTIVE:To observe the efficacy and safety of ferrous succinate in the treatment of pregnancy complicated with iron deficiency anemia. METHODS:90 pregnant women with iron deficiency anemia were randomly divided into treatment group and control group. All patients were stopped drugs related to iron supplement 2 weeks before treatment,and the blood index-es were detected,including red blood cell count (RBC),hemoglobin concentration (Hb) and serum ferritin concentration (SF), etc. The treatment group was orally given 2 Ferrous succinate tablets after a meal,twice a day;control group was orally given 2 Ferrous sulfate tablets after a meal,twice a day. The treatment course for both groups was 1 month. The clinic data was observed, including clinical efficacy,RBC,Hb and SF level before and after treatment,and the incidence of adverse reactions. RESULTS:The total effective rate in treatment group was significantly higher than control group,the difference was statistically significant(P0.05). CONCLUSIONS:Ferrous succinate tablets has good efficacy and safety in the treatment of pregnancy complicated with iron deficiency anemia.