Biliary tract infection and risk factors of patients with malignant obstructive jaundice / 复旦学报（医学版）

ABSTRACT

Objective To investigate the information obtained by bile culture and susceptibility testing as while factors like styles of obstruction,abdominal surgical history,degree and time of jaundice related to bacterial infection of biliary tract for patients with malignant obstructive jaundice (MOJ).Methods A total of 93 patients with MOJ received percutaneous transhepatic biliary drainage (PTBD) during Jan.,2015 and Mar.,2016.Bile specimens were collected during the procedure for bacterial culture and susceptibility.Results A rate of 60.2％ (56/93) patients had a positive bile culture and 58 strains were identified,in which gram-positive bacteria accounted for 36.2 ％ (21/58) and gram-negative bacteria accounted for 63.8 ％ (37/58).The most common bacteria were Enterococcus Faecalis,Escherichia Coli,Klebsiella Pneumonia and Staphylococcus Epidermidis.Conclusions The bile cultures indicated that a different antibacterial therapy should be managed in the patients of biliary infection complicated by malignant biliary jaundice.Low obstruction and abdominal surgery history are independent factors related to infection,while time and degree of jaundice shows no relationship to infection.