An open label efficacy study of topical imiquimod 5% cream in the treatment of verruca vulgaris and verruca plana in Filipinos
Journal of the Philippine Dermatological Society
; : 44-50, 2008.
Article
em En
| WPRIM
| ID: wpr-632975
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND: Verrucae or warts, are benign epithelial growths caused by human papillomavirus (HPV) infection of the skin. They are unsightly and may affect a patient's quality of life, causing social embarrassment, discomfort, pain, and interference in certain activities. OBJECTIVE: To evaluate the efficacy and safety of imiquimod 5 percent cream for sixteen weeks in the treatment of verruca vulgaris and verruca plana in an open-label trial involving healthy immunocompetent Filipino patients of the Dermatology out-patient clinic of the Philippine General Hospital. METHODS: Imiquimod 5 percent cream was self-administered by patients with verruca vulgaris or verruca plana on their lesions, nightly for 16 weeks. Follow-up was done every two weeks to determine any change in size over time. Side effects were recorded. RESULTS: Complete clearance was seen in 31.8% of verruca vulgaris cases, with improvement seen in 59 percent of cases. Shorter duration of lesions was associated with clearance. Complete clearance was seen in only 1 out of 8 patients with verruca plana treated. Minor side effects were reported. CONCLUSION: Topical imiquimod 5 percent cream is a safe, well-tolerated, painless, convenient, patient-applied route which may be a preferred alternative treatment for verruca vulgaris.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Pacientes Ambulatoriais
/
Dor
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Filipinas
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Pele
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Verrugas
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Infecções por Papillomavirus
/
Dermatologia
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Aminoquinolinas
/
Hospitais Gerais
Aspecto:
Patient_preference
Limite:
Adolescent
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Adult
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Aged
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Female
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Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
Journal of the Philippine Dermatological Society
Ano de publicação:
2008
Tipo de documento:
Article