Research progress in correlation factor on fibrosis of proliferative diabetic retinopathy / 中华实验眼科杂志
Chinese Journal of Experimental Ophthalmology
; (12): 473-476, 2011.
Article
em Zh
| WPRIM
| ID: wpr-635505
Biblioteca responsável:
WPRO
ABSTRACT
The fibrovascular membrane of proliferative diabetic retinopathy(PDR)cause severe damage to the structure and function of eye.The pathogenesis and development of fibrovascular membrane are associated with muhipie cellular factors,such as transforming growth factor(TGF),connective tissue growth factor(CTGF),basic fibroblast growth factor(bFGF),vascular endothelial growth factor(VEGF),platelet-derived growth factor(PDGF),tumor necrosis factor(TNF),extracellular matrix(ECM),matrix metalloproteinases(MMPs),endothelin and chemotactic factor,etc..So,the molecular mechanism of fibrovascular membrane of PDR is extremely complex.The relationship of pathogenesis on the fibrosis of PDR to cytokines,extracellular matrix,MMPs and other factors were summarized.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Experimental Ophthalmology
Ano de publicação:
2011
Tipo de documento:
Article