Study on DNA Polymorphism Analysis Technique as an Evidence of Engraftment Status after Allogeneic Hematopoietic Stem Cell Transplantation / 实用儿科临床杂志
Journal of Applied Clinical Pediatrics
; (24)2004.
Article
em Zh
| WPRIM
| ID: wpr-638511
Biblioteca responsável:
WPRO
ABSTRACT
Objective To evaluate engraftment status of patients after allogeneic hematopoietic stem cell transplantation(Allo-HSCT) and prompt relapse of disease based on DNA polymorphism analysis technique.Methods Sixty-six cases were detected by DNA polymorphism analysis technique and 25 cases were monitored and analyzed dynamically during this period.Results After Allo-HSCT,48 patients obtained type of donors,but 13 patients did not; 5 patients showed mixed chimerism.Two cases of type of donors converted into mixed chimerism and 4 cases of mixed chimerism converted into type of donors after some time. The others' engraftment status did not change.Conclusion DNA polymorphism analysis technique can detect engraftment status of patients exactly, rapidly, which provides effective evidences of constitution for more clinical therapy projects.
Texto completo:
1
Base de dados:
WPRIM
Aspecto:
Implementation_research
Idioma:
Zh
Revista:
Journal of Applied Clinical Pediatrics
Ano de publicação:
2004
Tipo de documento:
Article