Expression of c-Fos Protein and Character of Mossy Fiber Sprouting in Hippocampus of Rat with Febrile Seizures / 实用儿科临床杂志
Journal of Applied Clinical Pediatrics
; (24)1986.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-638654
Biblioteca responsável:
WPRO
ABSTRACT
Objective To explore the expression of c-Fos protein and character of mossy fiber sprouting(MFS) in hippocampus of rat with febrile seizures(FS).Methods Thirty-six 21-day-old male Sprague-Dawley rats were randomly divided into FS group,febrile control(FG) group and normal control(NG) group.FS was established by hyperthermal bath.Immune histochemistry and(Timm′s) staining were used to examine the expression of c-Fos protein in CA1 region and MFS in CA3 region of hippocampus.Results Excessive expression of c-Fos protein presented in the hippocampal CA1 region of FS group.The surface area percentage of c-Fos protein of FS group[(2.26?0.23)%] was higher than that of FG group[(1.08?0.19)%] and NG group[(0.71?0.14)%],there were significant difference between FS group and the other two groups(?~2=10.48 P
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Applied Clinical Pediatrics
Ano de publicação:
1986
Tipo de documento:
Artigo