Nuclear Factor Kappa B Involed in Immunologic Function of Critically Ill Newborns / 实用儿科临床杂志
Journal of Applied Clinical Pediatrics
; (24)2006.
Article
em Zh
| WPRIM
| ID: wpr-639428
Biblioteca responsável:
WPRO
ABSTRACT
Objective To observe the immunologic function of critically ill newborn and the relative function of nuclear factor kappa B(NF-?B).Methods The critically ill group contained 50 cases,and 25 cases from healthy newborns were used as control group.Blood samples were collected in each case,levels of cytokine interleukin(IL)-4,interferon(IFN)-?,tumor necrosis factor(TNF)-? and NF-?B were detected.Result Compared with control group,NF-?B of the critically ill newborn activated and the cytokine were disorder,and IL-4 and TNF-? increased,but IFN-? decreased.Conclusions Critically ill newborn exist immune functional disorder.Furthermore,NF-?B activation may be involved in the process in infants with critically illness.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of Applied Clinical Pediatrics
Ano de publicação:
2006
Tipo de documento:
Article