Clinical Implications of Genetic Testing for Hereditary Breast and Ovarian Cancer Syndrome in the Era of Genomic Medicine: Clinician's Perspectives
Journal of Breast Disease
; (2): 1-9, 2016.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-646631
Biblioteca responsável:
WPRO
ABSTRACT
Hereditary breast and ovarian cancer syndrome accounts for approximately 5% to 10% of breast or ovarian cancers, with which the high-penetrant BRCA1/2 genes have been associated. With the recent development of next-generation sequencing (NGS), germline mutation testing and its related medical and surgical management have been rapidly changing. In this review, we summarize the current status and perspectives of NGS testing for not only BRCA1/2 but also the other breast and ovarian cancer susceptibility genes.
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
Problema de saúde:
Meta 3.4: Reduzir as mortes prematuras devido doenças não transmissíveis
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Neoplasias Ovarianas
/
Mama
/
Neoplasias da Mama
/
Testes Genéticos
/
Mutação em Linhagem Germinativa
/
Sequenciamento de Nucleotídeos em Larga Escala
/
Síndrome Hereditária de Câncer de Mama e Ovário
Idioma:
Coreano
Revista:
Journal of Breast Disease
Ano de publicação:
2016
Tipo de documento:
Artigo