A Case of Milk-Alkali Syndrome in a Patient with Hypoparathyroidism after Total Thyroidectomy / 대한이비인후과학회지

ABSTRACT

Milk-alkali syndrome (MAS) is a disorder featuring hypercalcemia, renal failure and metabolic alkalosis due to ingestion of large amounts of calcium and absorbable alkali. MAS was first reported after Milk-alkali treatment of peptic ulcer in early 1910. But since the late 20th century, the wide availability and increasing consumption of calcium carbonate and vitamin D supplementation mostly for osteoporosis prevention has been noted as reemerging clinical backgrounds of MAS. We experienced a case of a woman who had taken calcium and vitamin D for a year due to hypoparathyroidism after total thyroidectomy. She was admitted suffering from nausea, vomiting, anorexia and irritability with the triad of hypercalcemia, metabolic alkalosis and acute renal insufficiency. Every abnormal symptom, calcium level and renal function were normalized with fluid and diuretic therapies.