Effect of Cephalosporins on Growth Plates of Femoral Heads of Rats / 대한정형외과학회잡지
The Journal of the Korean Orthopaedic Association
; : 351-356, 1999.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-653857
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE:
To study the effect of ceftezole Na on the matrix of femoral epiphyseal plates. MATERIALS ANDMETHODS:
Rats were intraperitoneally injected with ceftezole Na (1500 mg/kg B.W) was every day for a week. The specimens obtained from the femoral head were stained with alcian blue (pH 2.5)-P.A.S. to detect the distribution of acid and neutral mucopolysaccharides, and ultrastructural studies for growth plates were also performed.RESULTS:
We found that interterritorial and territorial matrices of treatment groups were weakly stained than that of control groups and dilatation and sacculation were observed in rough endoplasmic reticulums in the chondrocyte of the treated group.CONCLUSIONS:
According to the histochemical and ultrastructural research, ceftezole Na induces a decrease in mucosubstances in the chondrocytes of growth plate.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Cefalosporinas
/
Retículo Endoplasmático Rugoso
/
Condrócitos
/
Dilatação
/
Azul Alciano
/
Glicosaminoglicanos
/
Lâmina de Crescimento
/
Cabeça
Limite:
Animais
Idioma:
Coreano
Revista:
The Journal of the Korean Orthopaedic Association
Ano de publicação:
1999
Tipo de documento:
Artigo