Evaluation of the effects of splenectomy in treating chronic immuno thrombocytopenic purpurea

ABSTRACT

From Aug-2000 to Aug-2003 at HCM City Blood Transfusion and Hematology hospital, 31 cases of endoscopic splenectomy were studied to evaluate the effect of this surgery to treat chronical immuno-thrombocytopenic purpurea once corticotherapy and immunosupressive therapy failed. Results showed that one year after splenectomy, 64,52 – 76,92%, and 2 years after, 50% of cases had had completely positive response. There was absolute failure in 38,7% of cases within 3 first months, but from the 4th month, there was no relapse case. A half number of patients with failed splenectomy had had quick response to corticotherapy more.The duration of treatment was short, endoscopic splenectomy was safe. There was no death. No case of blood transfusion was needed. There were no complications