Effects of total laparoscopic thyroid subtotal resection on intraoperative incision length and postoperative serum Tg and VEGF levels in patients with early differentiated thyroid carcinoma / 实用医学杂志

ABSTRACT

Objective To investigate the effect of total laparoscopic thyroid subtotal resection in early differentiation thyroid carcinoma. Methods Seventy-two patients with early differentiated thyroid cancer from November 2013 to September 2016 weredivided into groups according to the random number table methods,with 36 cases in each group.Control group was treated with open thyroidectomy,and study group total laparoscopic thyroid subtotal resection.Patients′condition at the first day after operation,the level changes of serum VEGF and Tg levels at the first day at admission and after operation and aesthetic effect of operation were compared between 2 groups. Results There were shorter incision length,lower pain score and less intraoperative blood loss in study group when compared with those in control group,and the operation time was shorter than that in control group(P<0.05).The number of lymph node dissection in study group was not significantly different from that in control group(P>0.05). The levels of serum VEGF and Tg in 2 groups were lower than those before the operation,and the levels of all indexes in study group were lower than those in control group(P < 0.05). The total satisfaction of aesthetic effect (97.22%)in study group was higher than that of control group(75.00%)(P < 0.05). Conclusions Total endoscopic thyroid subtotal resection is effective for the treatment of early differentiation of thyroid cancer with small incisionand less postoperative pain. It can effectively reduce serum Tg and VEGF levels and improve the surgical aesthetic satisfaction.