MicroRNA and Helicobacter pylori-associated gastric carcinoma / 国际肿瘤学杂志

ABSTRACT

Helicobacter pylori infection can cause a series of microRNAs (miRNAs) disorders.These abnormal expressions of miRNAs can participate in the genesis and development of Helicobacter pylori-associated gastric carcinoma through regulating cell proliferation,differentiation and apoptosis.Identifying the targets and regulatory pathways of various miRNAs in the development of Helicobacter pylori-associated gastric cancer will provide a new direction for early diagnosis,prognosis and individualized treatment of gastric cancer.