Rapid Detection of Ephedrine in Biyan Sprays with Fourier Transmittance Near-infrared Spectroscopy / 中国药师
China Pharmacist
; (12): 156-158, 2015.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-669734
Biblioteca responsável:
WPRO
ABSTRACT
Objective:
To establish a rapid analysis method for determining the content of ephedrine in Biyan sprays.Methods:
The FT-NIR spectra of the samples were collected by near-infrared liquid transmission spectroscopy. Using the HPLC analysis values as the reference, a quantitative analysis model for ephedrine was established with partial least square ( PLS) , the first derivative and Nor-ris smooth was used in the spectra pretreatment, and 6 136. 38-5 364. 99 cm-1 and 7 038. 90-6 969. 48 cm-1 were selected as the fre-quency ranges.Results:
R2 and RMSEC of the calibration set was 0. 992 6 and 1. 20, respectively. R2 and RMSEP of the vallidation set was 0. 993 5 and 1. 28, respectively. R2 and RMSEP of the cross validation set was 0. 986 9 and 1. 60, respectively.Conclusion:
The method is rapid and non-desturctive, and can be applied in the rapid assessment and online examination of the quality of Biyan sprays.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo diagnóstico
Idioma:
Chinês
Revista:
China Pharmacist
Ano de publicação:
2015
Tipo de documento:
Artigo