Expression and heterogeneity of epidermal growth factor receptor in human salivary gland mucoepidermoid carcinoma MEC-1 cells / 实用口腔医学杂志
Journal of Practical Stomatology
; (6)2000.
Article
em Zh
| WPRIM
| ID: wpr-670555
Biblioteca responsável:
WPRO
ABSTRACT
Objective: To study the expressien and heterogeneity of epidenmoid growth factor receptor(EGFR) in human mucoepidermoid carcinoma MEC 1 cells. Methods: EGFR1 McAb (MaH) immunofluorescent stain and flowcytometer (FCM) were used to detect the positive percentage and heterogeneity of EGFR expression in MEC 1 cells. Results: Positive expression of EGFR was found in 100% of MEC 1 cells. Average peak channel of relative fluorescent intensity was 8.006?4.410. Double peaks of MEC 1 cells from single parameter histogram was observed with FCM. Conclusion: All MEC 1 cells express EGFR and there are heterogeneous cell populations of EGFR expression in MEC 1 cell line.
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1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of Practical Stomatology
Ano de publicação:
2000
Tipo de documento:
Article