Feasibility Study of Test Method for Histamine-like Substances in Aclarubicin Hydrochloride / 中国药师
China Pharmacist
; (12): 1885-1887,1898, 2015.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-671177
Biblioteca responsável:
WPRO
ABSTRACT
Objective:
To establish a test method for histamine-like substances in aclarubicin hydrochloride.Methods:
According to the method in the appendix of Chinese Pharmacopoeia ( edition 2010 ) , the test of histamine-like substances was carried out. Re-sultsThe test of histamine-like substances was not interfered by aclarubicin hydrochloride with the concentration below 0. 01 mg· ml-1 . Histamine-like substances in 4 batches of samples were determined by the established method, and the results were consistent with those of the test method for depressor substances.Conclusion:
The test method for histamine-like substances is feasible with the limit of 1 μg·mg-1 .
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Pharmacist
Ano de publicação:
2015
Tipo de documento:
Artigo