Epidemiological survey on rotavirus diarrhea among children in Dongguan area / 国际检验医学杂志

ABSTRACT

Objective To investigate the epidemiologic features of rotavirus (RV)diarrhea among children in Dongguan area. Methods The stool specimens were collected from the children outpatients with acute diarrhea in the enterology clinic of our hospi-tal from June 2012 to May 2013.The cluster A RV antigen was detected in the stool specimens by the qualitative technique of col-loidal gold and immunochromatographic double antibody sandwich assay.The sex,age of onset and seasons distribution were ana-lyzed.Results Among 4 967 cases of diarrhea,1 555 cases (33.8%)were positive for rotavirus antigen.The ratio of infected boys and girls was 1 .9∶1 .Most infected children (93%)were under the age of three.The cases of RV diarrhea were observed through-out the year;and it was found that there were two peaks of detection rate appearing in November (49.8%)and February (43.3%), and it was lowest in June and October (16.0%).Conclusion Children aged under 3 years in Dongguan area are the susceptible pop-ulation for cluster A RV.RV diarrhea occurs throughout the year with two peaks in spring and autumn-winter.Timely RV vaccina-tion for children based on the epidemiologic features is effective for reducing the incidence of RV diarrhea.