The association analysis of TAP1 gene, Fc?RI? gene with asthma and its phenotype / 中国免疫学杂志

ABSTRACT

Objective:In order to known the relationship between TAP1 gene , Fc?RI?gene and the development of asthma Methods:The microsatellite——TAP1 inside the intron of TAP1 gene and the RFLP locus inside the intron of Fc?RI?gene were choiced to study in asthma patients using the Amp FLP and RFLP method Results:The allele of Fc?RI?gene is associated with asthma and BHR, there is not relationship between TAP1 and asthma Conclusion:Fc?RI?gene may be important candidate gene susceptibility to asthma TAP1 gene may not participate in the development of asthma