Effects of benazepril on apoptosis and expression of Bax and Bcl-2 in kidney of diabetic rats with different blood glucose levels / 中华内分泌代谢杂志

ABSTRACT

Diabetic rats were induced by intraperitoneal injection of streptozotocin.TUNEL and immunohistochemistry results showed that the renal tubular cell apoptosis index(AI)and Bax protein expression were significantly reduced,and the Bcl-2 protein expression in glomeruli was significantly increased in diabetic rats with stable hyperglycemia treated by benazepril compared with diabetic rats with stable hyperglycemia treated by vehicle(all P