Determination of in vitro Percutaneous Rate and in vitro of Release of Compound Patch of Hyperosteogeny / 中成药
Chinese Traditional Patent Medicine
; (12)1992.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-681105
Biblioteca responsável:
WPRO
ABSTRACT
Objective:
To study the feasibility of percutaneous absorption of Compound Patch of Hyperosteogeny(CPH).Methods:
The content of ferulic acid,an index composition in percutaneous receptor fluid and release receptor fluid were determined by HPLC.Results:
The results of in vitro transdermal delivery experiment and in vitro release experiment showed that ferulic acid permeated at the constant speed of 0.2142?g?cm -2 ?h -1 in 24 hours and its release coincided with Higuchi Equation.Futhermore,the release rate was 14.53?g?cm -2 ?h -1/2 .Conclusion:
CPH is a skeleton controlledtransdermal delivery system whose permeation speed is limited by skin.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Traditional Patent Medicine
Ano de publicação:
1992
Tipo de documento:
Artigo