Protective effects of angiotensin Ⅱ receptors antagonist on the LPS-induced lung acute injury / 中华急诊医学杂志
Chinese Journal of Emergency Medicine
; (12)2006.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-683293
Biblioteca responsável:
WPRO
ABSTRACT
Objective To investigate the effects of angiotensinⅡ(AngⅡ) receptors antagonist on the LPS-induced acute lung injury (ALl).Method Wistar rats were randomly divided into three groupscontrol group;in LPS group,mrs were treated with LPS (10 mg/kg) at 3,6,12,and 24 hours;in LPS+ AngⅡreceptors antagonist group,pre-expasure to AngⅡreceptors antagonist [Sar~1,Ile~8] AngⅡfor 30 minutes before treated with LPS (10 mg/kg) for 6 hours.All the rats were killed,and the lung tissue was collected.Results Compared with control group pulmonary wet/dry weight ratio was significantly higher in the other two groups (P
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Emergency Medicine
Ano de publicação:
2006
Tipo de documento:
Artigo