IN VITRO EFFECT OF TINIDAZOLE ON TRICHOMONAS VAGINALIS AND TRICHOMONAS HOMINIS / 中国寄生虫学与寄生虫病杂志

ABSTRACT

The trichomonadicidal activity of tinidazole (Fasigyn) was evaluated by the ire vitro cultivation of Trichomonas vaginalis and Trichomonas hominis with different drug concentrations. The results showed that, after 48-hour incubation with tinidazole, the 100% lethal concentration was 20?g/ml. The trichomonadicidal effect of tinidazole was one titre lower than that of metronidazole. With regard to T. hominis, after 48-hour incubation with tinidazole, the 100% lethal concentration was 20?g/ml. In comparison with metronidazole, the trichomonadicidal effect of tinidazole was similar.