Effect of sufficient nutritional support on nutritional status and quality of life in cancer patients following chemotherapy / 肠外与肠内营养

ABSTRACT

Objective: To compare the effects of routine nutritional support and sufficient nutritional support on nutritional status and quality of life in patients with cancer undergoing chemotherapy. Methods: From February 2016 to February 2017, 86 patients with cancer undergoing chemotherapy were collected, and the nutritional risk was assessed by Nutritional Risk Screening Tools and Patient-Generated-Subjective Global Assessment. The included patients were randomized given conventional nutritional support and sufficient nutritional support (n=43 each group). At the end of chemotherapy, the effects of different nutrition support on the nutritional status and quality of life were evaluated via nutritional risk screening tools, quality of life scale, the BMI, and the level of serum total protein, serum albumin and hemoglobin. Results: The nutritional support was successfully completed both groups. In terms of nutritional status, the nutritional risk screening score was statistically significant among the nutrition support group before and after chemotherapy, and routine nutrition support group after chemotherapy (P ＜ 0. 05). In addition, the level of serum albumin and hemoglobin in the sufficient nutritional support group were significantly higher than those before chemotherapy (P ＜ 0. 05). The quality of life score, physical function, emotional function, life quality, overall symptom scale fatigue, nausea, insomnia, loss of appetite, constipation, and diarrhea in the sufficient nutrition support group were lower than those in the conventional nutritional support group (P ＜ 0. 05). Conclusions: The sufficient nutritional support can effectively improve the nutritional status and the quality of life in cancer patients with nutritional risk after chemotherapy.