Research advances in secreted protein acidic and rich in cysteine in hepatocellular carcinoma / 临床肝胆病杂志

ABSTRACT

Primary liver cancer is a common malignant tumor in clinical practice,and secreted protein acidic and rich in cysteine (SPARC) plays a very important role in the progression and metastasis of liver cancer.This article introduces the structure and biological function of SPARC and analyzes its mechanism of action in malignant tumors and its association with the progression and metastasis of liver cancer,as well as the perspectives of its application in the diagnosis and treatment of liver cancer.