Study on the correlation between clinical factors and recurrence time in patients with breast cancer after mastectomy / 临床外科杂志

ABSTRACT

Objective To study the relationship between postoperative recurrence time and relat-ed clinical factors in patients with breast cancer. Methods The clinical data of 170 patients with recur-rent breast cancer were analyzed retrospectively. The recurrence time and the related influencing factors were analyzed using Kaplan-Meier test. Results The one-way analysis of variance showed that endocrine therapy,estrogen receptor and progesterone receptor(ERPR)status,Ki-67 and lymph node metastasis were related to the recurrence time(P < 0. 05). Pearson correlation analysis showed that age,neutrophil-to-lym-phocyte ratio(NLR)and platelet-to-lymphocyte(PLR)were related to the recurrence time(P < 0. 05). Fi-nally,Cox multivariate analysis showed that endocrine therapy,lymph node metastasis and Ki-67 were in-dependent prognostic factors of relapse(P < 0. 05). Conclusion To develop personalized follow-up and adjuvant treatment strategy according to the characteristics of patients may prevent breast cancer from re-currence.