Analysis of long-term outcomes and causes influencing visual prognosis in eyes receiving anti-VEGF-A for wet age-related macular degeneration / 中华实验眼科杂志

ABSTRACT

As a progressive chronic disease,age-related macular degeneration (AMD) is the leading cause of blindness worldwide.However,current therapy for AM D shows a dramatic breakthrough.More and more patients with AMD undergo intravitreous injection of anti-vascular endothelial growth factor A (VEGF-A) regimen,which has been demonstrated a beneficial therapeutic treatment to improve visual acuity in a short period.The long-term outcomes have come into focus considering prolonged treatment cycle and follow-up period.The long-term outcomes and safety of anti VEGF-A will be reviewed in this article contributing to investigate the causes influencing prognosis of visual acuity after anti VEGF-A treatment.