The relationship between fragmented QRS complexes and severity of coronary artery lesion in elder patients with complex coronary artery lesions / 中华老年医学杂志

ABSTRACT

Objective To investigate the relationship between fragmented QRS (fQRS) complexes and the severity of coronary artery lesions in elder patients with complex coronary artery lesions.Methods Two-hundred and one elder patients with complex coronary lesions undergone coronary angiography in Beijing Anzhen Hospital from January 2013 to July 2016 were enrolled.Based on the coronary lesions,patients were divided into the complex coronary lesions group and the simple coronary lesions group.The clinical features and coronary scores were compared between groups.Logistic regression analysis was used to evaluate the risk factors of complex coronary lesions.Results Compared with simple coronary lesions group,the complex coronary lesions group was associated with higher rate of fQRS (31.3％ vs.17.2％,x2 =9.68,P＜0.01),more number of fQRS leads [(1.0±1.5) vs.(0.5±0.8),t=-4.04,P＜0.01],longer duration of QRS [(87.2±10.7) ms vs.(84.1±8.9) ms,t=-3.09,P＜0.01].Moreover,patients with fQRS had a lower level of high density lipoprotein cholesterol (HDL-C) [M(Q25,Q75),0.9 (0.8,1.1) mmol/L vs.1.0 (0.9,1.2) mmol/L,t=-2.84,P＜0.01] and a higher Gensini score [40 (8-76) vs.22 (16-2),t=8.63,P＜0.01] compared with those without fQRS.Furthermore,Logistic regression analysis showed that HDL C (OR=0.346,95％CI0.163 0.674,P＜0.05),fQRS (OR=2.215,95％ CI1.381-3.725,P＜0.05) and the number of fQRS leads (OR=4.613,95％ CI2.412-9.578,P＜0.05) were independent risk factors for patients with high Gensini score,and there was a positive correlation between fQRS and Gensini scores (=0.624,P＜0.01).Conclusions fQRS might be a noninvasive indicator of severity of coronary artery lesions for elder patients with complex coronary lesions.