Clinical and reflectance confocal microscopy features of 11 cases of extragenital lichen sclerosus et atrophicus / 中华皮肤科杂志

ABSTRACT

Objective To investigate clinical and reflectance confocal microscopy(RCM)features of extragenital lichen sclerosus et atrophicus.Methods Clinical data and RCM images were collected from 11 patients with extragenital lichen sclerosus et atrophicus in Department of Dermatology of Shenyang No.7 People's Hospital and the First Hospital of China Medical University between October 2010 and October 2016,and retrospectively analyzed.Results Of the 11 patients,9 were female,and 6 had lesions on the neck.RCM imaging showed atrophy of the epidermis,disappearance of high reflectivity and circular structures in the basal layer,blurred dermo-epidermal junction,highly reflective quasi-circular big cells and a few mononuclear cells scattering in the superficial dermis,and homogenization and increased density of collagen.Conclusion Extragenital lichen sclerosus et atrophicus has characteristic RCM presentation.