Clinical analysis of classification and prognosis of ischemic-type of biliary lesions after liver transplantation / 中华器官移植杂志

ABSTRACT

Objective To classify the ischemic-type of biliary lesions (TTBL) after liver transplantation based on the imaging findings and the severity of the clinical manifestations,and analyze the relationship between the grading and prognosis of ITBL.Methods 886 liver transplantation recipients were divided into 2 groups:ITBL group (124 cases),and non-ITBL group (762 cases).The prognosis of the recipients was compared between the two groups.According to the severity of ITBL,ITBL patients were divided into three grades,and the prognosis was compared among the three grades.Results The survival rate,graft survival rate and adverse prognosis rate between ITBL group and non-ITBL group were statistically significant (P＜0.001).There was no significant difference in survival rate among mild,moderate and severe ITBL groups.There was very significant difference in graft survival between mild and moderate group versus severe group (P＜0.05).There was no significant difference between mild and moderate groups in graft survival.There was significant difference in the incidence of adverse outcomes between mild group versus moderate and severe groups (P＜0.04),but there was no significant difference between the moderate and severe groups.Conclusion The ITBL classification based on the imaging severity of the biliary tract and the level of bilirubin can predict the prognosis of ITBL.