The likelihood of achieving pregnancy through timed coitus in young infertile women with decreased ovarian reserve / 대한생식의학회지
Clinical and Experimental Reproductive Medicine
; : 31-37, 2018.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-713342
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
To evaluate the pregnancy rate and time to pregnancy after timed coitus with or without superovulation in infertile young women younger than 35 years old with low serum anti-Müllerian hormone (AMH) levels (< 25th percentile).METHODS:
A total of 202 patients younger than 35 years old were recruited retrospectively between 2010 and 2012. Ninety-eight women had normal serum AMH levels (25–75th percentile), 75 women had low serum AMH levels (5th≤&< 25th percentile) and 29 women had very low serum AMH levels (< 5th percentile), according to reference values for their age group.RESULTS:
The clinical pregnancy rate was positively associated with AMH levels, but this trend did not reach statistical significance (43.9% vs. 41.3% vs. 27.6% in the normal, low, and very low AMH groups, respectively). The time to pregnancy was longer in the very low AMH group than in the normal AMH group (13.1±10.9 months vs. 6.9±6.1 months, p=0.030). The cumulative live birth rate over 18 months was lower in the very low AMH group than in the normal AMH group, with marginal significance (20.0% vs. 55.9%, p=0.051). The duration of infertility was negatively correlated with achieving pregnancy (odds ratio, 0.953; 95% confidence interval, 0.914–0.994; p=0.026).CONCLUSION:
Conservative management, such as timed coitus with or without superovulation, should be considered in young patients who have low ovarian reserve without any infertility factors. However, for women with a long duration of infertility or very low serum AMH levels, active infertility treatment should be considered.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Valores de Referência
/
Superovulação
/
Estudos Retrospectivos
/
Idade Materna
/
Coito
/
Taxa de Gravidez
/
Nascido Vivo
/
Hormônio Antimülleriano
/
Tempo para Engravidar
/
Reserva Ovariana
Tipo de estudo:
Estudo observacional
Limite:
Feminino
/
Humanos
/
Gravidez
Idioma:
Inglês
Revista:
Clinical and Experimental Reproductive Medicine
Ano de publicação:
2018
Tipo de documento:
Artigo