Successful Treatment of Cisplatin Overdose with Plasma Exchange
Yonsei Medical Journal
; : 128-132, 2002.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-71367
Biblioteca responsável:
WPRO
ABSTRACT
We report a 48-year-old man with laryngeal cancer who received a massive cisplatin toxic overdose without intravenous prehydration through an error in prescription. He received 400 mg/m2 of cisplatin over a 4-day period. On day 4, he exhibited a broad range of cisplatin toxicities and emergency plasma exchange was started. From day 5 through 19, he underwent 9 cycles of plasma exchange and his plasma cisplatin concentration decreased from 2,470 ng/ml to 216 ng/ml. He completely recovered without any sequelae. No previous reports exist in the English literature of survival without complication after the administration of such a high cisplatin dosage without prehydration.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Troca Plasmática
/
Cisplatino
/
Overdose de Drogas
/
Pessoa de Meia-Idade
/
Antineoplásicos
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Yonsei Medical Journal
Ano de publicação:
2002
Tipo de documento:
Artigo