Organoid as a culture system for viral vaccine strains
Clinical and Experimental Vaccine Research
; : 145-148, 2018.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-716054
Biblioteca responsável:
WPRO
ABSTRACT
Organoid is an in vitro multicellular form mimicking in vivo organ. Its similarity to human organ including cellular organization, molecular expression patterns, as well as genetic signatures enables to study the characteristics of infectious agents and host-pathogen interaction. For the features of organoid, this system also can be potentially used to cultivate currently uncultivable viruses of vaccine candidates. This paper will briefly describe problems in the current culture system for virus production and the possibility of organoid as culture system for viral vaccine and their current limitations that should be solved to meet the goal.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Cultura de Vírus
/
Técnicas In Vitro
/
Vacinas Virais
/
Organoides
/
Interações Hospedeiro-Patógeno
Limite:
Humanos
Idioma:
Inglês
Revista:
Clinical and Experimental Vaccine Research
Ano de publicação:
2018
Tipo de documento:
Artigo