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A Case of Moderate Hidradenitis Suppurativa and Psoriasis Treated with Secukinumab
Annals of Dermatology ; : 462-464, 2018.
Artigo em Inglês | WPRIM (Pacífico Ocidental) | ID: wpr-716498
Biblioteca responsável: WPRO
ABSTRACT
Hidradenitis suppurativa (HS) is a disorder of the apocrine gland causing a chronic, recurrent and painful inflammation. It is a disabilitating condition and, though many therapeutic options are available, the response is often ineffective in most cases and patients can present many recurrences with physical and psychological sequelae. Recent data had shown increased interleukin (IL)-17 serum levels in patients with HS. Psoriasis is a chronic immune-mediated inflammatory disorder and new evidences have shown the role of Th17 cells in its pathogenesis and the therapeutic efficacy of anti-IL-17 antibodies. We present a case of a patient suffering from psoriasis and HS successfully treated with anti-IL-17 antibodies for both conditions. This is the first case report of HS treated with secukinumab.
Assuntos

Texto completo: Disponível Base de dados: WPRIM (Pacífico Ocidental) Assunto principal: Glândulas Apócrinas / Psoríase / Recidiva / Interleucinas / Hidradenite / Hidradenite Supurativa / Interleucina-17 / Células Th17 / Inflamação / Anticorpos Limite: Humanos Idioma: Inglês Revista: Annals of Dermatology Ano de publicação: 2018 Tipo de documento: Artigo
Texto completo: Disponível Base de dados: WPRIM (Pacífico Ocidental) Assunto principal: Glândulas Apócrinas / Psoríase / Recidiva / Interleucinas / Hidradenite / Hidradenite Supurativa / Interleucina-17 / Células Th17 / Inflamação / Anticorpos Limite: Humanos Idioma: Inglês Revista: Annals of Dermatology Ano de publicação: 2018 Tipo de documento: Artigo
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