Liquid Biopsy: Current Status and Future Perspective in Gastric Cancer and Helicobacter Infection / 대한Helicobacter연구학회지
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
; : 150-156, 2018.
Article
em Ko
| WPRIM
| ID: wpr-716953
Biblioteca responsável:
WPRO
ABSTRACT
Precision medicine stands for 4Ps - precise, preventive, participatory, and personal; in which “precision” is important because the current modern medicine starts from “trial and error,” and “one does not fit all”. Current targeted therapies for cancer have changed treatment approaches and led the precision medicine; however, clinical use of liquid biopsy, using blood or other liquid specimens to characterize circulating tumor cells (CTC) or tumor genes instead of biopsies of tumor tissues, still awaits availability of more information regarding non-invasive cancer detection and characterization, prediction of treatment response, monitoring the disease course and relapse possibilities, identification of mechanisms of drug resistance, and newer pathogenesis. In this review, we will introduce the basic concept of CTC, circulating cell free DNA, and exosomes and their possible application for gastric cancer relevant with Helicobacter pylori infection.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Recidiva
/
Neoplasias Gástricas
/
Biópsia
/
DNA
/
Resistência a Medicamentos
/
Helicobacter pylori
/
Infecções por Helicobacter
/
Helicobacter
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História Moderna 1601-
/
Exossomos
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
Ko
Revista:
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Ano de publicação:
2018
Tipo de documento:
Article