A Case of Iatrogenic Wernicke's Encephalopathy Following Chemotherapy and Total Parenteral Nutrition / 대한혈액학회지
Korean Journal of Hematology
; : 95-99, 2001.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-720327
Biblioteca responsável:
WPRO
ABSTRACT
Wernicke's encephalopathy is a neuropsychiatric condition generally caused by acute thiamine deficiency. Although it is common in the severe alcoholics, several other causes also have been identified, such as total parenteral nutrition (TPN) use, persistent vomiting, hyperemesis gravidarum, anorexia nervosa and malnutrition. The classic triad of Wernicke's encephalopathy are ataxia, altered mentation and ophthalmoplegia. A 19-year-old boy had been treated with high dose Ara-C and mitoxantrone for acute myelogenous leukemia and intravenous hyperalimentation due to persistent vomiting. He suddenly complained of diplopia, gait disturbance and generalized weakness at 36th day after chemotherapy. Physical examinations showed disorientated mentality, oculomotor palsy and horizental nystagmus. The diagnosis of Wernicke's encephalopathy was made with classical brain MRI and decreased thiamine level. The patient was successfully treated with vitamin B1. We presented a case of acute Wernicke's encephalopathy developed after high dose Ara-C chemotherapy followed by intravenous hyperalimentation in a patient with acute myelogenous leukemia.
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
ODS3 - Meta 3.5 Prevenção e tratamento do consumo de substâncias psicoativas
Problema de saúde:
Meta 3.5 Prevenção e tratamento do consumo de substâncias psicoativas
/
Álcool
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Paralisia
/
Exame Físico
/
Ataxia
/
Tiamina
/
Deficiência de Tiamina
/
Vômito
/
Encefalopatia de Wernicke
/
Encéfalo
/
Imageamento por Ressonância Magnética
/
Leucemia Mieloide Aguda
Tipo de estudo:
Estudo diagnóstico
Aspecto:
Determinantes sociais da saúde
Limite:
Feminino
/
Humanos
/
Masculino
/
Gravidez
Idioma:
Coreano
Revista:
Korean Journal of Hematology
Ano de publicação:
2001
Tipo de documento:
Artigo