Primary Signet Ring Cell Carcinoma of the Lung: Report of Two Cases / 대한세포병리학회지
Korean Journal of Cytopathology
; : 83-86, 1997.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-726394
Biblioteca responsável:
WPRO
ABSTRACT
Signet ring cell carcinoma is a variant of adenocarcinoma and has been rarely reported in the lung as a primary site. Recently, we experienced two cases of primary signet ring cell carcinoma in the lung without any other extrapulmonary lesion. Sputum cytology was performed and the tumor cells which have eccentrically located nuclei and abundnat mucinous cytoplasm were dispersed in diffuse sheets. On resected specimen, the signet ring cells occupied about 50~80% of all tumor cell nests. HIstochemical staining revealed that the mucin produced by tumor cells was mostly carboxylated acid mucins. Ultrastructurally, the tumor cells contained variable sized membrane-bound mucin granules with weak central osmiophilic density and showed numerous surface microvilli, which represented that tumor cells arose from bronchial epithelial cells. In general, this tumor has diffusely infiltrative nature and the prognosis is fatal due to widespread metastasis before clinical discovery.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prognóstico
/
Escarro
/
Adenocarcinoma
/
Carcinoma de Células em Anel de Sinete
/
Citoplasma
/
Células Epiteliais
/
Pulmão
/
Microvilosidades
/
Mucinas
/
Metástase Neoplásica
Tipo de estudo:
Estudo prognóstico
Idioma:
Coreano
Revista:
Korean Journal of Cytopathology
Ano de publicação:
1997
Tipo de documento:
Artigo