Adverse Drug Reaction in the Neonatal Intensive Care Unit: A Single Center Study
Neonatal Medicine
; : 187-191, 2015.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-72970
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE:
Little research has been conducted on adverse drug reactions in neonates, particularly in Korea, where no studies have been reported.METHODS:
We conducted a retrospectively study using medical records in a neonatal intensive care unit from August 1, 2013 to July 31, 2014. The adverse drug reactions were evaluated according to the Naranjo algorithm, World Health Organization-Uppsala Monitoring Centre, and the Korean adverse drug reaction algorithm.RESULTS:
Of the 410 infants hospitalized during the study period, 57 cases of adverse drug reactions were reported in 40 infants (9.8%). The average gestational age was 28.4+/-4.3 weeks, the average birth weight was 1,184.1+/-622.0 g, and the adverse drug reactions were reported at an average of 21.0+/-29.7 days after birth. Causative agents were identified as electrolytes (36.8%), respiratory medication (14.0%), total parenteral nutrition (12.3%), lipid emulsion (10.5%), antibiotics (7.0%), non-steroidal anti-inflammatory drugs (NSAIDs, 7.0%), sedatives (7.0%), vaccine (3.5%), and an antiviral medication (1.8%). Of the 57 cases, 55 (96.5%) cases demonstrated meaningful adverse drug reactions, defined as those given a score of "possible or above" in all 3 adverse drug reaction algorithms.CONCLUSION:
More emphasis is warranted in the field of neonatal adverse drug reactions.
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
Problema de saúde:
Meta 3.8 Atingir a cobertura universal de saúde
/
Meta 3.7 Acesso universal aos serviços de saude reprodutiva
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Peso ao Nascer
/
Terapia Intensiva Neonatal
/
Prontuários Médicos
/
Saúde Global
/
Estudos Retrospectivos
/
Idade Gestacional
/
Nutrição Parenteral Total
/
Parto
/
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos
/
Eletrólitos
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
/
Lactente
/
Recém-Nascido
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Neonatal Medicine
Ano de publicação:
2015
Tipo de documento:
Artigo