Immunohistochemical detection of melatonin receptor subtype in the adrenal corte x of the human embryo / 第二军医大学学报

ABSTRACT

Objective: To investigate the potential role of me latonin in the adrenal cortex of human embryo. Methods:Specifi c melatonin receptors was localized and characterized in the adrenal cortex of h u man embryo by means of immunohistochemistry. Results: mt1 （Me l1a）and MT2 （Mel1b）subtype of melatonin receptors was principally localize d to cytoplasm in zona glomerulosa， fasciculata and reticularis. Conclu sion It is possible that mt1 and MT2 subtype of melatonin receptors co-exist in the adrenal cortex of human embryo.