A Case of Lithium-Induced Nephrogenic Diabetes Insipidus and Rhabdomyolysis / 대한내과학회지
Korean Journal of Medicine
; : 367-370, 2012.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-741073
Biblioteca responsável:
WPRO
ABSTRACT
A 59-year-old woman was admitted to our hospital with polydipsia and general weakness. She had a 30-year history of bipolar disorder and was being treated with risperidone (4 mg/day) and lithium carbonate (1,200 mg/day). During her time in hospital, her urine output and serum osmolality increased, and her urine osmolality decreased. She was found to have myoglobulinuria, an elevated creatine kinase level, and abnormal renal function. Based on these findings, the patient was diagnosed with diabetes insipidus and rhabdomyolysis secondary to lithium therapy. After fluid therapy and the withdrawal of lithium, her clinical symptoms improved significantly. Her urine volume decreased gradually after treatment with amiloride. The effects of lithium on the muscle system are unknown. Hyperosmolarity caused by lithium-induced diabetes insipidus is considered a contributing factor in rhabdomyolysis.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Concentração Osmolar
/
Rabdomiólise
/
Transtorno Bipolar
/
Carbonato de Lítio
/
Diabetes Insípido Nefrogênico
/
Risperidona
/
Creatina Quinase
/
Diabetes Insípido
/
Polidipsia
/
Hidratação
Limite:
Feminino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Medicine
Ano de publicação:
2012
Tipo de documento:
Artigo